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Stem Cell Transplantation Virginia Oncology
Associates
Peripheral Blood Stem Cell Transplantation (PBSCT)
is a relatively new medical procedure that is used to
treat diseases once thought to be incurable. PBSCT’s
have been used to treat patients diagnosed with leukemia,
aplastic anemia, lymphomas (such as Hodgkin’s disease),
multiple myeloma, immune deficiency disorders and some
solid tumors, such as breast and ovarian.
The process begins with an office procedure where stem
cells are collected from the blood stream in several daily
sessions lasting 2-3 hours. This is called apheresis.
The blood is moved through a machine that removes some
of the stem cells and returns the rest of the blood to
the body. The stem cells are then frozen and stored until
the time they are given back to the patient, later on
in the transplant.
The patient receives high dose chemotherapy to destroy
the cancer cells in the body. Following high dose chemotherapy,
the stem cells are thawed and given back to the patient
intravenously, like a simple blood transfusion. After
2-3 weeks, the stem cells begin producing new white
blood cells, red blood cells and platelets. With improved
methods of treatment and transplant experience, it is
now possible for the patient to remain out of the hospital
for part or all of the transplant procedure. Stem cell
collection, high dose chemotherapy and the supportive
therapies needed during recovery are all given in our
office. During the transplant, at least one family member
or friend will be the caregiver. Physical and emotional
support during this time is crucial.
We will work closely with the patient to understand
your special needs and address any concerns. The transplant
lasts approximately 5-6 weeks. During that time, we
will coordinate all care.
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